Tap into the full potential of small RNA transcriptomics with miRVEL Small RNA-Seq
Small RNA Sequencing
Small RNAs (sRNAs) are short (<200 nt), non-coding RNA molecules and key regulators of gene expression at the post-transcriptional level. Small RNAs are implicated in a broad spectrum of biological processes, including development, differentiation, signaling pathways, responses to environmental stimuli, infection and aging, as well as the pathogenesis of cancer and other diseases.
Small RNA sequencing (sRNA-Seq) has become a powerful tool for cancer research, developmental biology, and plant science, providing valuable insights into sRNA-mediated regulatory circuits and underlying molecular mechanisms.
What is the aim of your sRNA-Seq study?
Our validated workflows and service packages for small RNA-Seq analysis include advanced solutions for biomarker research and sRNA discovery studies, as well as cost-efficient, high-throughput sRNA expression profiling solutions.
Applications
sRNA-Seq provides comprehensive, unbiased insights into the sRNA transcriptome of various organisms and has numerous applications. Dysregulated sRNAs may serve as potential diagnostic and prognostic biomarkers for various diseases. In plants, sRNA-Seq helps uncover the regulatory networks involved in stress responses, pathogen resistance, and developmental processes, which provides invaluable information for crop improvement and biotechnology.
sRNA-Seq is commonly used to study:
- sRNA expression profiling
- Discovery and characterization of new sRNAs
- Mode-of-action for post-transcriptional regulation
- Discovery of novel biomarkers for cancer and other diseases
- Drug discovery and target screens
- Small RNA kinetics
Benefits
miRVEL Small RNA-Seq family offers convenient and fast protocols and dedicated solutions for all your scientific needs, including:
- Advanced solution for sRNA discovery and biomarker studies (ultimate sensitivity, ideal for biofluids)
- Cost-efficient sRNA profiling kit (routine use, validation studies)
- Unique technology for functional sRNA isolation
- Small RNA sequencing services and data analysis
Access low-input samples
miRVEL Small RNA-Seq libraries accommodate a broad range of RNA input, starting from as little as 1 ng.
Convenient gel-free protocol
miRVEL libraries efficiently prevent adapter-dimer formation, eliminating the need for laborious gel-size selection and thus significantly reducing hands-on time and workflow duration.
UDIs
Unique dual indices UDIs guarantee accurate read assignment and minimize the risk of read misassignment due to index hopping.
End-to-end solution
Find the right sRNA-Seq solution for you: start with TraPR, the unique technology for functional sRNA isolation, then select the perfect sRNA-Seq library prep, or opt for our NGS and data analysis services.
Ready to get started?
Establish your sRNA-Seq workflow specifically for your application with Lexogen’s sRNA solutions or send your samples to our NGS Services facility. Fill out the form below to consult with our experts:
