The comprehensive overview article about the Lexogen SIRVs (Spike-In RNA Variant Control Mixes) has been published in CoreGenomics blog. It explains what are the SIRVs, how they are made, used and analyzed. The article also covers such aspects as usage of SIRVs in bulk as well as single cell RNA-Seq, and how they are comparable with other spike-in controls.
Read the complete article: http://core-genomics.blogspot.co.at/2016/10/sirvs-rna-seq-controls-from-lexogen.html