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Lexogen Launches Quantitative RNA-Seq Service for Cost-efficient and Accurate Gene Expression Profiling

March 1st, 2017|

Press release

Austria – March 1st, 2017 – Today Lexogen, a transcriptomics and next generation sequencing […]

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Upgrades of the Lexogen RNA-Seq Library Prep Kits

February 16th, 2017|

QuantSeq for Illumina for Ultra-High Throughput
QuantSeq 3’ mRNA-Seq Library Prep has already been widely used […]

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The results of the Lexogen Research Award – “Controlling RNA-Seq Experiments Using SIRVs”

December 7th, 2016|

This autumn we have held our second in 2016 Lexogen Research Award. This […]

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Dual Indexing Add-on Kit for Lexogen RNA-Seq library preparations: up to 384 barcodes for QuantSeqTM and SENSETM kits

December 5th, 2016|

Lexogen introduces a dual-indexing system for the Illumina-compatible versions of its RNA-Seq library preparation kits. […]

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Welcome

Lexogen is a biotech company focusing on RNA and complete transcriptome studies using next generation sequencing technologies.

We have been at the forefront of RNA research since 2007, and our technologies and products are being used by thousands of scientists all over the world. “Lexo” in Greek means “word”, and Lexogen stands for the word of genes, which is the transcriptome. We strive to be the pioneers in this fascinating field of RNA science, and together with the fastest-growing technology of the past years, the next generation sequencing (NGS), we are sure that we can make a big contribution to the world.

Our Products

RiboCop rRNA Depletion Kit V1.2 (Human/Mouse/Rat)

RiboCop rRNA Depletion Kit V1.2 (Human/Mouse/Rat) enables removal of ribosomal RNA from total RNA and is suited for Next Generation Sequencing as well as other demanding RNA analysis applications.

SIRVs (Spike-in RNA Variant Control Mixes)

The SIRVs are a set of transcript variants designed to validate the performance of isoform-specific RNA sequencing workflows, enabling bioinformatic algorithms to quantify, map, and assemble isoforms with exceptionally high accuracy.

SENSE Total and mRNA-Seq Library Prep Kits

SENSETM Total RNA/mRNA-Seq Library Prep Kits generate ready-to-sequence libraries with exceptional strand-specificity from low amounts of input RNA within a few hours. SENSE mRNA-Seq Library Prep Kits are available for Illumina and Ion Torrent sequencing platforms. An automated SENSE mRNA-Seq Library Prep can be performed on the PerkinElmer Sciclone/Zephyr NGS workstations. SENSE Total RNA-Seq Library Prep Kit is available for Illumina sequencing platforms.

QuantSeq Expression Profiling Library Prep Kits

QuantSeq kits enable cost-efficient sequencing by counting. These kits are an exceptional alternative to standard RNA-Seq and microarrays. Just one fragment per transcript is produced and therefore there is no need for length normalization. This makes data analysis very simple and accurate. Up to 384 samples can be multiplexed in one lane, saving your sequencing space. QuantSeq is available for 3’ mRNA-Seq and targeted RNA-Seq.

QuantSeq 3′ mRNA-Seq Library Prep Kit FWD is the best solution for genome-wide gene expression analysis by sequencing towards the poly(A) tail. The kit is available for Illumina and Ion Torrent platforms.

QuantSeq 3′ mRNA-Seq Library Prep Kit REV for Illumina is designed in a way that NGS reads start directly at the 3’ end of transcripts, enabling detailed 3’ UTR analysis and the study of alternative polyadenylation.

QuantSeq-Flex Targeted RNA-Seq Library Prep Kit V2 is designed to make Illumina compatible libraries from any RNA sample using custom primers. It is open for development by advanced RNA-Seq users based on their custom needs.

TeloPrime Full-Length cDNA Amplification Kit

TeloPrimeTM Full-Length cDNA Amplification Kit generates full-length cDNA from total RNA. It is highly selective for full-length RNA molecules that are both capped and polyadenylated and therefore no cDNA from degraded RNA is being produced. The full-length cDNA products can be further used for various downstream applications such as NGS, RACE, cloning, microarray probes, and normalization.

SPLIT RNA Extraction Kit

SPLITTM RNA Extraction Kit enables a fast and highly efficient extraction of RNA that is free of genomic DNA contamination. The RNA can be recovered as total RNA or split into a large and a small RNA fraction, facilitating the analysis of e.g. mRNA and miRNA from the same sample. Thus the protocol is ideal for seamlessly preparing libraries for NGS of total RNA or its large and small fractions.

What our clients say

“We have successfully used the Lexogen QuantSeq FWD kit for the preparation of RNAseq libraries over the last year. The kit provides us with a highly cost effective and reliable, fast solution to generate RNAseq libraries that we subsequently use to assess gene expression levels and most importantly to rapidly compile and assess alternative cleavage and polyadenylation profiles. QuantSeq is a cornerstone for our RNAseq based research, in particular as multiplexing allows us to combine it with cost effective sequencing on the Ion Torrent platform.”
André Furger,
Associate Professor, Chromosomal and RNA Biology, Department of Biochemistry, University of Oxford, UK
“With Lexogen Poly(A) Selection kit I was able to isolate reasonable amount of polyadenylated RNA with no trace of rRNA contamination. I see great advantages of this kit in clear-cut protocol and quite low starting concentration of total RNA that you can easily scale-up based on chosen downstream application. The other thing that should be appreciated is Lexogen customer service that provides you with very high level of support.”
Květoslava Brožinová,
Research Technician, Research Group: ERA Chair – RNA and Immunity, CEITEC, Brno, Czech Republic
“Lexogen has developed a cutting edge, fast and efficient RNA-seq library prep kit. The Lexogen SENSE kit enabled our lab to generate high quality RNA-seq data with no previous experience.”
Matt Thomson,
Center for Systems and Synthetic Biology,
University of California, San Francisco, USA

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