Latest News

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QuantSeq-Flex targeted RNA-Seq V2: Upgrade brings streamlined protocol and increased specificity

November 22nd, 2016|

Lexogen’s QuantSeq-Flex kit provides a protocol to generate Illumina-compatible libraries from total RNA within […]

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Controlling RNA-Seq Experiments Using Spike-In RNA Variants

October 20th, 2016|

Yesterday we had a webinar “Controlling RNA-Seq Experiments Using Spike-In RNA Variants. In this talk […]

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Gene expression RNA-Seq data analysis becomes simpler with the collaboration of Lexogen and Bluebee.

October 19th, 2016|

Press release

Vienna, Austria & Rijswijk, The Netherlands – October 19, 2016 – Today […]

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CoreGenomics blog article ‘’SIRVs: RNA-Seq controls from @Lexogen’’

October 17th, 2016|

The comprehensive overview article about the Lexogen SIRVs (Spike-In RNA Variant Control Mixes) has been […]

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Welcome

Lexogen is a biotech company focusing on RNA and complete transcriptome studies using next generation sequencing technologies.

We have been at the forefront of RNA research since 2007, and our technologies and products are being used by thousands of scientists all over the world. “Lexo” in Greek means “word”, and Lexogen stands for the word of genes, which is the transcriptome. We strive to be the pioneers in this fascinating field of RNA science, and together with the fastest-growing technology of the past years, the next generation sequencing (NGS), we are sure that we can make a big contribution to the world.

Our Products

RiboCop rRNA Depletion Kit V1.2 (Human/Mouse/Rat)

RiboCop rRNA Depletion Kit V1.2 (Human/Mouse/Rat) enables removal of ribosomal RNA from total RNA and is suited for Next Generation Sequencing as well as other demanding RNA analysis applications.

SIRVs (Spike-in RNA Variant Control Mixes)

The SIRVs are a set of transcript variants designed to validate the performance of isoform-specific RNA sequencing workflows, enabling bioinformatic algorithms to quantify, map, and assemble isoforms with exceptionally high accuracy.

SENSE Total and mRNA-Seq Library Prep Kits

SENSETM Total RNA/mRNA-Seq Library Prep Kits generate ready-to-sequence libraries with exceptional strand-specificity from low amounts of input RNA within a few hours. SENSE mRNA-Seq Library Prep Kits are available for Illumina, Ion Torrent, and SOLiD sequencing platforms. An automated SENSE mRNA-Seq Library Prep can be performed on the PerkinElmer Sciclone/Zephyr NGS workstations. SENSE Total RNA-Seq Library Prep Kit is available for Illumina sequencing platforms.

QuantSeq Expression Profiling Library Prep Kits

QuantSeq kits enable cost-efficient sequencing by counting. These kits are an exceptional alternative to standard RNA-Seq and microarrays. Just one fragment per transcript is produced and therefore there is no need for length normalization. This makes data analysis very simple and accurate. Up to 96 samples can be multiplexed in one lane, saving your sequencing space. QuantSeq is available for 3’ mRNA-Seq and targeted RNA-Seq.

QuantSeq 3′ mRNA-Seq Library Prep Kit for rapid generation of Illumina and Ion Torrent compatible libraries of the sequences close to the 3’end of the polyadenylated RNA.

QuantSeq-Flex Targeted RNA-Seq Library Prep Kit is designed to make Illumina compatible libraries from any RNA sample using custom primers. It is open for development by advanced RNA-Seq users based on their custom needs.

TeloPrime Full-Length cDNA Amplification Kit

TeloPrimeTM Full-Length cDNA Amplification Kit generates full-length cDNA from total RNA. It is highly selective for full-length RNA molecules that are both capped and polyadenylated and therefore no cDNA from degraded RNA is being produced. The full-length cDNA products can be further used for various downstream applications such as NGS, RACE, cloning, microarray probes, and normalization.

SPLIT RNA Extraction Kit

SPLITTM RNA Extraction Kit enables a fast and highly efficient extraction of RNA that is free of genomic DNA contamination. The RNA can be recovered as total RNA or split into a large and a small RNA fraction, facilitating the analysis of e.g. mRNA and miRNA from the same sample. Thus the protocol is ideal for seamlessly preparing libraries for NGS of total RNA or its large and small fractions.

What our clients say

“We really enjoyed using the Lexogen SENSE kit for the SOLiD platform. For moderately low input samples it took only one day to complete the protocol and simplified library preparation greatly. The kit yielded strand specific sequence information and eliminated the need to preselect for poly A RNA, while still giving a very low percentage of rRNA reads in the final data. We are anxious to try the new version for our ION Torrent platforms as well.”
Caitlin Costelle,
Senior Research Assistant, Molecular Resource Center, The University of Tennessee Health Science Center, Memphis, TN, USA
“With Lexogen Poly(A) Selection kit I was able to isolate reasonable amount of polyadenylated RNA with no trace of rRNA contamination. I see great advantages of this kit in clear-cut protocol and quite low starting concentration of total RNA that you can easily scale-up based on chosen downstream application. The other thing that should be appreciated is Lexogen customer service that provides you with very high level of support.”
Květoslava Brožinová,
Research Technician, Research Group: ERA Chair – RNA and Immunity, CEITEC, Brno, Czech Republic
“Lexogen has developed a cutting edge, fast and efficient RNA-seq library prep kit. The Lexogen SENSE kit enabled our lab to generate high quality RNA-seq data with no previous experience.”
Matt Thomson,
Center for Systems and Synthetic Biology,
University of California, San Francisco, USA

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